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SIGLEC9 Mouse anti-Human, Clone: OTI8F7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF500380

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Siglec9 (Sialic acid-binding Ig-like lectin 9) is single-pass type I membrane protein and belongs to immunoglobulin super family and contains two Ig-like C2 type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. It is reported that Siglec9 recognizes sialic acid in alpha2, 3-or alpha2, 6-glycosidic linkage to galactose. Using a specific antibody, Siglec9 was found to be expressed at high or intermediate levels by monocytes, neutrophils, and a minor population of CD16+, CD56- cells. Siglec9 also acts as an inhibitory receptor for MUC16 that attenuates T- andNK cell function. Recent reports suggest that Siglec9 expressed on DCs is involved in immuno regulation through ligation with mucins in an epithelial cancer patient.Specifications
SIGLEC9 | |
Monoclonal | |
Unconjugated | |
SIGLEC9 | |
CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9 | |
Mouse | |
Affinity Chromatography | |
RUO | |
27180 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI8F7 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9Y336 | |
SIGLEC9 | |
Full length human recombit protein of human SIGLEC9 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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