Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA521433

Invitrogen™ SIK2 Monoclonal Antibody (4C6)
GREENER_CHOICE

Catalog No. PIMA521433
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA521433 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA521433 Supplier Invitrogen™ Supplier No. MA521433
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

Peptide Sequence: AHAFEAFQST RSGQRRHTLS EVTNQLVVMP GAGKIFSMND SPSLDSVDSE YDMGSVQRDL NFLEDNPSLK DIMLANQPSP RMTSPFISLR PTNPAMQALS SQKREVHNRS.

SNF1LK2 (QIK) is a serine/threonine kinase and is a salt-inducible kinase that belongs to the AMP-activated protein kinase family. SNF1LK2 negatively regulates CRE-binding protein (CREB) activity by phosphorylating the CREB-specific coactivator transducer of regulated CREB activity (TORC). SIK2 is thought to be part of a signaling cascade that regulates the expression and activity of the insulin-induced genes PGC-1'alpha and UCP-1 in brown adipocytes, impairment of which has been implicated in obesity and insulin resistance in human and animal models. SIK2 has also been reported as a key regulator for neuronal survival after ischemia, suppressing CREB-mediated gene expression after oxygen-glucose deprivation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIK2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 4C6
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene SIK2
Gene Accession No. Q9H0K1
Gene Alias G630080D20Rik; KIAA0781; LOH11CR1I; QIK; Qin-induced kinase; RGD1559698; salt induceable kinase 2; salt inducible kinase 2; salt-inducible kinase 2; salt-inducible protein kinase 2; salt-inducible serine/threonine kinase 2; serine/threonine-protein kinase SIK2; Serine/threonine-protein kinase SNF1-like kinase 2; Sik2; SIK-2; SNF1-like kinase 2; SNF1LK2
Gene Symbols SIK2
Host Species Mouse
Immunogen SIK2 (NP_056006, 467 a.a. ~ 576 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23235
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.