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Invitrogen™ SIKE Polyclonal Antibody
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Catalog No. PIPA555247
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100 μL
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PIPA555247 100 μL
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Catalog No. PIPA555247 Supplier Invitrogen™ Supplier No. PA555247
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AEPVLKAHQS HSAEIESQID RICEMGEVMR KAVQVDDDQF CKIQEKLAQL ELENKELREL LSISSESLQA RKENSMD Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 90%.

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIKE
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SIKE1
Gene Accession No. Q9BRV8
Gene Alias 2810005O12Rik; 5730470L24Rik; AI450236; AI839862; RGD1311316; SIKE; SIKE1; Sikeb; suppressor of IKBKE 1; suppressor of IKK epsilon; suppressor of IKK-epsilon
Gene Symbols SIKE1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SIKE. Recombinant protein control fragment (Product #RP-93990).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80143
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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