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Invitrogen™ SIKE Polyclonal Antibody
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Catalog No. PIPA5100210
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100 μL
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PIPA5100210 100 μL
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Catalog No. PIPA5100210 Supplier Invitrogen™ Supplier No. PA5100210
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SIKE1.

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIKE
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SIKE1
Gene Accession No. Q9BRV8
Gene Alias 2810005O12Rik; 5730470L24Rik; AI450236; AI839862; RGD1311316; SIKE; SIKE1; Sikeb; suppressor of IKBKE 1; suppressor of IKK epsilon; suppressor of IKK-epsilon
Gene Symbols SIKE1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SIKE1(Accession Q9BRV8), corresponding to amino acid residues V156-I206.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80143
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

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