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Invitrogen™ SIKE Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100210

Catalog No. PIPA5100210


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Description

Description

Antibody detects endogenous levels of total SIKE1.

Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SIKE
Polyclonal
Unconjugated
SIKE1
2810005O12Rik; 5730470L24Rik; AI450236; AI839862; RGD1311316; SIKE; SIKE1; Sikeb; suppressor of IKBKE 1; suppressor of IKK epsilon; suppressor of IKK-epsilon
Rabbit
Affinity chromatography
RUO
80143
-20°C
Liquid
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q9BRV8
SIKE1
A synthesized peptide derived from human SIKE1(Accession Q9BRV8), corresponding to amino acid residues V156-I206.
100 μL
Primary
Human
Antibody
IgG
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