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Invitrogen™ SIKE Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5100210
Description
Antibody detects endogenous levels of total SIKE1.
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.
Specifications
SIKE | |
Polyclonal | |
Unconjugated | |
SIKE1 | |
2810005O12Rik; 5730470L24Rik; AI450236; AI839862; RGD1311316; SIKE; SIKE1; Sikeb; suppressor of IKBKE 1; suppressor of IKK epsilon; suppressor of IKK-epsilon | |
Rabbit | |
Affinity chromatography | |
RUO | |
80143 | |
-20°C | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
Q9BRV8 | |
SIKE1 | |
A synthesized peptide derived from human SIKE1(Accession Q9BRV8), corresponding to amino acid residues V156-I206. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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