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SiliCycle™ SiliaBond™ Functionalized Silica Gels, Cyanoborohydride (CBH), 40 to 63 μm, 60 Å

Our Cyanoborohydride (Si-CBH) is very useful in reductive amination and in the reduction of imines and aldehydes.

Supplier:  SiliCycle™ R66730B250G

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Catalog No. 01-184-390

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SiliaBond™ Cyanoborohydride (Si-CBH) is the silica-bound equivalent of sodium cyanoborohydride. Bound cyanoborohydride is very useful in reductive amination and in the reduction of imines and aldehydes. Cyanide contamination of products is a concern when using the solution phase equivalent. This problem is minimized with the use of silica-bound materials, since the toxic cyanide residue remains on the silica. Additionally, it may be used to reduce α, β-unsaturated carbonyl to the corresponding unsaturated alcohol.

To determine if any cyanide ion was leaching from the silica, 1 g of SiliaBond™ Cyanoborohydride was washed in 10 mL of methanol for 24 hours. Cyanide strips indicated less than 3 ppm in each test performed.



Reductive Amination and Reduction of Imines and Aldehydes
250 g
40 to 63 μm
Bulk Functionalized Irregular Silica Gel
60 Å
Cyanoborohydride (CBH)
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