Invitrogen™ SIM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116187

Catalog No. PIPA5116187

Description

SIM1 Polyclonal Antibody for Western Blot, IHC (P)

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis, it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.

Specifications

• Antigen: SIM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIM1
• Gene Alias: BHLHE14; bHLH-PAS transcription factor; Class E basic helix-loop-helix protein 14; mSIM1; SIM bHLH transcription factor 1; SIM bHLH transcription factor 1a; sim1; sim1a; single-minded 1; single-minded family bHLH transcription factor 1; single-minded family bHLH transcription factor 1a; single-minded homolog 1; single-minded homolog 1 (Drosophila); single-minded homolog 1-A; single-minded-like 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6492
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.43 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P81133
• Gene Symbols: SIM1
• Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIM1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov