Invitrogen™ SIN3A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581022

Catalog No. PIPA581022

Description

This antibody has specificity for Human Sin3a.

Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in the transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B. Containing 4 paired amphipathic helix domains (PAH domains), mSin3A and mSin3B have been shown to directly interact with several other transcriptional repressor proteins including HDAC1, HDAC2, RbAp46, the methyl CpG binding protein MeCP2, the Mad/Max heterodimer, and the corepressors silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) and nuclear receptor corepressor (N-CoR).

Specifications

• Antigen: SIN3A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIN3A
• Gene Alias: AW553200; Histone deacetylase complex subunit Sin3a; Kiaa4126; Mammalian Sin3A; mKIAA4126; mSin3A; Paired amphipathic helix protein Sin3a; SIN; Sin3; SIN3 homolog A, transcription regulator; SIN3 transcription regulator family member A; SIN3 transcription regulator homolog A; SIN3A; transcriptional corepressor Sin3a; transcriptional co-repressor Sin3A; transcriptional regulator, SIN3 yeast homolog A; transcriptional regulator, SIN3A; transcriptional regulator, SIN3A (yeast)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 25942
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q96ST3
• Gene Symbols: SIN3A
• Immunogen: A synthetic peptide corresponding to the N-terminus of the Human Sin3a.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG