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Invitrogen™ SIN3B Monoclonal Antibody (2C11)
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Catalog No. PIMA521444
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100 μg
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PIMA521444 100 μg
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Catalog No. PIMA521444 Supplier Invitrogen™ Supplier No. MA521444
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Mouse Monoclonal Antibody

Peptide Sequence: HKMVFIVNSE DYMYRRGTLC RAKQVQPLVL LRHHQHFEEW HSRWLEDNVT VEAASLVQDW LMGEEDEDMV PCKTLCETVH VHGLPVTRYR VQYSRRPA.

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIN3B
Applications ELISA
Classification Monoclonal
Clone 2C11
Concentration 0.2-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene SIN3B
Gene Accession No. O75182
Gene Alias 2810430C10Rik; Histone deacetylase complex subunit Sin3b; KIAA0700; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator family member B; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; transcriptional regulator, SIN3B; transcriptional regulator, SIN3B (yeast)
Gene Symbols SIN3B
Host Species Mouse
Immunogen SIN3B (NP_056075.1, 1063 a.a. ~ 1160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23309
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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