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Invitrogen™ SIN3B Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA575568
Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Specifications
SIN3B | |
Polyclonal | |
Unconjugated | |
SIN3B | |
2810430C10Rik; Histone deacetylase complex subunit Sin3b; KIAA0700; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator family member B; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; transcriptional regulator, SIN3B; transcriptional regulator, SIN3B (yeast) | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
20467, 23309 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 | |
O75182, Q62141 | |
SIN3B | |
Synthetic peptide corresponding to amino acids 260-305 of Human SIN3B. | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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