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Invitrogen™ SIN3B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575568

Catalog No. PIPA575568


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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SIN3B
Polyclonal
Unconjugated
SIN3B
2810430C10Rik; Histone deacetylase complex subunit Sin3b; KIAA0700; Paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; SIN3 homolog B, transcriptional regulator; SIN3 transcription regulator family member B; SIN3 transcription regulator homolog B; SIN3B; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; transcriptional regulator, SIN3B; transcriptional regulator, SIN3B (yeast)
Rabbit
Antigen affinity chromatography
RUO
20467, 23309
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
O75182, Q62141
SIN3B
Synthetic peptide corresponding to amino acids 260-305 of Human SIN3B.
100 μL
Primary
Human, Mouse
Antibody
IgG
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