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Invitrogen™ Sintilimab Recombinant Human Monoclonal Antibody
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Catalog No. PIMA542220
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100 μg
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PIMA542220 100 μg
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Catalog No. PIMA542220 Supplier Invitrogen™ Supplier No. MA542220
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Description

Human Recombinant Monoclonal Antibody

Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Sintilimab is a fully human anti-PD-1 antibody for tumor immunotherapy. It adopts IgG4 molecular framework and modified its hinge region sequence (S228P). Sintilimab, as a programmed death receptor 1 (PD-1) blocker, can bind to PD-1 molecules on the surface of T cells and relieve the inhibitory effect of PD-1 pathway on T cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Sintilimab
Applications ELISA, SDS-Page
Classification Recombinant Monoclonal
Concentration 1.57 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene Alias IBI-308
Host Species Human
Immunogen Human PDCD1/PD1/CD279.
Purification Method Protein A/G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG4 κ
Target Molecule Chemical
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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