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Invitrogen™ SIPA1 Polyclonal Antibody
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Catalog No. PIPA588447
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100 μL
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PIPA588447 100 μL
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Catalog No. PIPA588447 Supplier Invitrogen™ Supplier No. PA588447
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ESGRPRRSFS ELYTLSLQEP SRRGAPDPVQ DEVQGVTLLP TTKQLLHLCL QDGGSPPGPG DLAEERTEFL HSQNSLSPRS SLSDEAPVLP NTTPDLLLAT TAKPSVPSAD SETPLTQDRP GSPSGSEDKG NPAPELRASF LPRTLSLRNS ISRIMSEAGS GTLEDEWQAI SEIASTCNTI LESLSREGQP IPESGDPKGT PKSDAEPEPG NLSEKVSHLE SMLRKLQEDL QKEKADRAAL EEEVRSLRHN NRRLQAESES AATRLLLASK QLGSPTADLA; Positive Samples: Raji, K-562, HeLa, LO2, Mouse spleen; Cellular Location: Cytoplasm, Endomembrane system, Nucleus, Peripheral membrane protein, perinuclear region.

The product of this gene is a mitogen induced GTPase activating protein. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIPA1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.53 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene SIPA1
Gene Accession No. P46062, Q96FS4
Gene Alias GTPase-activating protein Spa-1; MGC102688; MGC17037; p130 SPA-1; signal-induced proliferation associated gene 1; signal-induced proliferation-associated 1; signal-induced proliferation-associated gene 1; signal-induced proliferation-associated protein 1; SIPA1; Sipa-1; SPA1
Gene Symbols SIPA1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1 (NP_69498529).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20469, 6494
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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