Invitrogen™ SIPA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558957

Catalog No. PIPA558957

Description

Immunogen sequence: SPSGSEDKGN PAPELRASFL PRTLSLRNSI SRIMSEAGSG TLEDEWQAIS EIASTCNTIL ESLSREGQPI PESGDPKGTP KSDAEPEPGN LSEKVSHLES M Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 82%.

The product of this gene is a mitogen induced GTPase activating protein. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Specifications

• Antigen: SIPA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIPA1
• Gene Alias: GTPase-activating protein Spa-1; MGC102688; MGC17037; p130 SPA-1; signal-induced proliferation associated gene 1; signal-induced proliferation-associated 1; signal-induced proliferation-associated gene 1; signal-induced proliferation-associated protein 1; SIPA1; Sipa-1; SPA1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6494
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96FS4
• Gene Symbols: SIPA1
• Immunogen: Recombinant protein corresponding to Human SIPA1. Recombinant protein control fragment (Product #RP-97563).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG