Invitrogen™ SIPA1L2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA565007

Catalog No. PIPA565007

Description

Immunogen sequence: SSPSNQSSSSD PGPGGSGPWR PQVGYDGCQS PLLLEHQGSG PLECDGARER EDTMEASRHP ETKWHGPPSK VLGSYKERAL QKDGSCKDSP NKLSHIGDKS CSSH Highest antigen sequence identity to the following orthologs - mouse 86%, rat 87%.

Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

Specifications

• Antigen: SIPA1L2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIPA1L2
• Gene Alias: BC058408; Kiaa0545; KIAA1389; mKIAA1389; serine-rich synapse associated protein 2; serine-rich synapse-associated protein; Sersap2; signal induced proliferation associated 1 like 2; signal-induced proliferation-associated 1 like 2; signal-induced proliferation-associated 1-like protein 2; Sipa1l2; SIPA1-like protein 2; SPA-1-like 2; SPAL2; Spar2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57568
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9P2F8
• Gene Symbols: SIPA1L2
• Immunogen: Recombinant Human SIPA1L2. Recombinant protein control fragment (Product #RP-105773).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov