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Invitrogen™ SIPA1L3 Polyclonal Antibody
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Catalog No. PIPA5140165
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100 μL
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PIPA5140165 100 μL
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Catalog No. PIPA5140165 Supplier Invitrogen™ Supplier No. PA5140165
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Description

Rabbit Polyclonal Antibody

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: QPSGSFSTPG SATYVRYKPS PERYTAAPHP LLSLDPHFSH DGTSSGDSSS GGLTSQESTM ERQKPEPLWH VPAQARLSAI AGSSGNKHPS R Highest antigen sequence indentity to the following orthologs: Rat - 89%, Mouse - 89%.

Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIPA1L3
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SIPA1L3
Gene Accession No. O60292
Gene Alias 2610511M17Rik; CTRCT45; KIAA0545; signal induced proliferation associated 1 like 3; signal-induced proliferation-associated 1 like 3; signal-induced proliferation-associated 1-like protein 3; Sipa1l3; SIPA1-like protein 3; SPA-1-like 3; SPA-1-like protein 3; Spal3; SPAR3
Gene Symbols SIPA1L3
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SIPA1L3. Recombinant protein control fragment (Product #RP-109447).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23094
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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