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Sipa1Rabbit anti-Human, Mouse, Rat, Polyclonal, Rockland™
SDP

Catalog No. 501991924
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100 μg
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Catalog No. Quantity
50-199-1924 100 μg
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Catalog No. 50-199-1924 Supplier Rockland Immunochemicals Supplier No. 600401A36
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Rabbit Polyclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody is specific for mouse Sipa1 protein. A BLAST analysis was used to suggest cross-reactivity with Sipa1 from mouse, human and rat based on a 100% homology with the immunizing sequence. Cross-reactivity with Sipa1 from other sources has not been determined.

The product of this gene is a mitogen induced GTPase activating protein. It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.

Specifications

Antigen Sipa1
Applications ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.25 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene SIPA1
Gene Accession No. P46062, Q96FS4
Gene Alias GTPase-activating protein Spa-1; MGC102688; MGC17037; p130 SPA-1; signal-induced proliferation associated gene 1; signal-induced proliferation-associated 1; signal-induced proliferation-associated gene 1; Signal-induced proliferation-associated protein 1; SIPA1; Sipa-1; SPA1
Gene Symbols SIPA1
Host Species Rabbit
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20469, 361710, 6494
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
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