Invitrogen™ SIRP gamma Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA521657

Catalog No. PIPA521657

Description

Recommended positive controls: K562. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.

Specifications

• Antigen: SIRP gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRPG
• Gene Alias: bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55423
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.9 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9P1W8
• Gene Symbols: SIRPG
• Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human CD172 gamma. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG