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Invitrogen™ SIRP gamma Polyclonal Antibody

Sheep Polyclonal Antibody

Supplier:  Invitrogen™ PA547627

Catalog No. PIPA547627


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Description

Description

In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) SIRP alpha, rhSIRP beta 1, and recombinant mouse SIRP alpha is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SIRP gamma
Polyclonal
Unconjugated
SIRPG
bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma
Sheep
Antigen affinity chromatography
RUO
55423
-20°C, Avoid Freeze/Thaw Cycles
Lyophilized
Flow Cytometry, Western Blot
0.2 mg/mL
PBS with 5% trehalose and No Preservative
Q9P1W8
SIRPG
CHO-derived recombinant human SIRP gamma/CD172g Val64-Ser364, (Val263Ala) and (Ser286Leu).
100 μg
Primary
Human
Antibody
IgG
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