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Invitrogen™ SIRP gamma Polyclonal Antibody
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Catalog No. PIPA547627
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100 μg
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Catalog No. Quantity
PIPA547627 100 μg
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Catalog No. PIPA547627 Supplier Invitrogen™ Supplier No. PA547627
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Description

Sheep Polyclonal Antibody

In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) SIRP alpha, rhSIRP beta 1, and recombinant mouse SIRP alpha is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRP gamma
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene SIRPG
Gene Accession No. Q9P1W8
Gene Alias bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma
Gene Symbols SIRPG
Host Species Sheep
Immunogen CHO-derived recombinant human SIRP gamma/CD172g Val64-Ser364, (Val263Ala) and (Ser286Leu).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55423
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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