Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. BDB752002

SIRP Gma (CD172g) Mouse, anti-Human, R718, Clone: OX-119, BD OptiBuild™

Catalog No. BDB752002 Shop All BD Biosciences Products
Change view
Click to view available options
Quantity:
50 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
BDB752002 50 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. BDB752002 Supplier BD Biosciences Supplier No. 752002
Add to Cart
Add to Cart

Description

Mouse Monoclonal Antibody

The OX-119 monoclonal antibody specifically recognizes Signal-regulatory protein gamma (SIRP-gamma or SIRPγ) which is also known as CD172g or Signal-regulatory protein beta 2 (SIRP-beta-2 or SIRPβ2). SIRPγ (CD172g) is a ∼55 kDa type I transmembrane glycoprotein that is encoded by SIRPG, which belongs to the SIRPβ2 subfamily within the Ig gene superfamily. The SIRPγ (CD172g) extracellular domain contains one amino-terminal IgV-like domain and two IgC-like domains, and a short cytoplasmic region with no known motifs. It is expressed on mature thymocytes, CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, all activated NK cells and some B cells. SIRPγ (CD172g) binds to CD47 (integrin-associated protein/IAP) that is widely expressed on most hematopoietic cells, epithelial cells, endothelial cells, fibroblasts and many tumor cell lines. SIRPγ (CD172g) may play a regulatory role in T cell-T cell interactions and may induce apoptosis through CD47.

TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRP Gma (CD172g)
Applications Flow Cytometry
Classification Monoclonal
Clone OX-119
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Refrigerate Upon Arrival
Form Liquid
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.