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Invitrogen™ SIRT2 Monoclonal Antibody (5H11H9)
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Catalog No. FERMA548713
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100 μg
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FERMA548713 100 μg
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Catalog No. FERMA548713 Supplier Invitrogen™ Supplier No. MA548713
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Mouse Monoclonal Antibody

SIRT2 Monoclonal Antibody for ELISA, Western Blot

The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRT2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 5H11H9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene SIRT2
Gene Accession No. Q8IXJ6
Gene Alias 5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2
Gene Symbols SIRT2
Host Species Mouse
Immunogen Purified recombinant fragment of human SIRT2 (AA: 275-389) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22933
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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