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Invitrogen™ SIRT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520490

Catalog No. PIPA520490


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20490 can be used with blocking peptide PEP-0610.

The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SIRT2
Polyclonal
Unconjugated
SIRT2
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; Sirt2; sirtuin 2; sirtuin type 2; sirtuin-2
Rabbit
Antigen Affinity Chromatography
RUO
22933, 361532, 64383
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q5RJQ4, Q8IXJ6, Q8VDQ8
SIRT2
A 17 amino acid peptide near the amino terminus of the human SIRT2.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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