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Invitrogen™ SIRT3 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA596406
Description
Positive Samples: SW620; Cellular Location: Mitochondrion matrix Immunogen sequence: PQRFLLHVVD FPMADLLLIL GTSLEVEPFA SLTEAVRSSV PRLLINRDLV GPLAWHPRSR DVAQLGDVVH GVESLVELLG WTEEMRDLVQ RETGKLDGPD K.
SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.
Specifications
SIRT3 | |
Polyclonal | |
Unconjugated | |
SIRT3 | |
2310003L23Rik; AI848213; HGNC:14931; hSIRT3; mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase; mitochondrial protein lysine deacetylase; mSIR2L3; NAD-dependent deacetylase sirtuin-3; NAD-dependent deacetylase sirtuin-3, mitochondrial; NAD-dependent protein deacetylase sirtuin-3; NAD-dependent protein deacetylase sirtuin-3, mitochondrial; regulatory protein SIR2 homolog 3; silent mating type information regulation 2, (S.cerevisiae, homolog)-like 3; silent mating type information regulation 2, S.cerevisiae, homolog 3; Sir2l3; sir2-like 3; SIR2-like protein 3; SIRT3; SIRT3L mitochondrial; sirtuin 3; sirtuin type 3 | |
Rabbit | |
Affinity chromatography | |
RUO | |
23410, 293615, 64384 | |
-20°C, Avoid Freeze/Thaw Cycles | |
Liquid |
ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8R104, Q9NTG7 | |
SIRT3 | |
A synthetic peptide corresponding to a sequence within amino acids 299-399 of human SIRT3 (NP_0363711). | |
100 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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