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Invitrogen™ SIRT4 Polyclonal Antibody
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Catalog No. PIPA596727
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PIPA596727 100 μL
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Catalog No. PIPA596727 Supplier Invitrogen™ Supplier No. PA596727
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Description

Rabbit Polyclonal Antibody

Positive Samples: Mouse liver, Mouse heart, Rat lung; Cellular Location: Mitochondrion matrix Immunogen sequence: IGLFVPASPP LDPEKVKELQ RFITLSKRLL VMTGAGISTE SGIPDYRSEK VGLYARTDRR PIQHGDFVRS APIRQRYWAR NFVGWPQFSS HQPNPAHWAL STWEKLGKLY WLVTQNVDAL HTKAGSRRLT ELHGCMDRVL CLDCGEQTPR GVLQERFQVL NPTWSAEAHG LAPDGDVFLS EEQVRSFQVP TCVQCGGHLK PDVVFFGDTV NPDKVDFVHK RVKEADSLLV VGSSLQVYSG YRFILTAWEK KLPIAILNIG PTRSDDLACL KLNSRCGELL PLIDP.

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRT4
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 6.79 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene SIRT4
Gene Accession No. Q8R216, Q9Y6E7
Gene Alias 4930596O17Rik; MGC130046; MGC130047; MGC57437; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; NAD-dependent deacetylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; regulatory protein SIR2 homolog 4; SIR2L4; sir2-like 4; SIR2-like protein 4; SIRT4; sirtuin 4; sirtuin type 4
Gene Symbols SIRT4
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23409, 304539, 75387
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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