Invitrogen™ SIRT4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596727

Catalog No. PIPA596727

Description

Positive Samples: Mouse liver, Mouse heart, Rat lung; Cellular Location: Mitochondrion matrix Immunogen sequence: IGLFVPASPP LDPEKVKELQ RFITLSKRLL VMTGAGISTE SGIPDYRSEK VGLYARTDRR PIQHGDFVRS APIRQRYWAR NFVGWPQFSS HQPNPAHWAL STWEKLGKLY WLVTQNVDAL HTKAGSRRLT ELHGCMDRVL CLDCGEQTPR GVLQERFQVL NPTWSAEAHG LAPDGDVFLS EEQVRSFQVP TCVQCGGHLK PDVVFFGDTV NPDKVDFVHK RVKEADSLLV VGSSLQVYSG YRFILTAWEK KLPIAILNIG PTRSDDLACL KLNSRCGELL PLIDP.

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Specifications

• Antigen: SIRT4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRT4
• Gene Alias: 4930596O17Rik; MGC130046; MGC130047; MGC57437; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent ADP-ribosyltransferase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; NAD-dependent deacetylase sirtuin-4; NAD-dependent protein deacetylase sirtuin-4; NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; regulatory protein SIR2 homolog 4; SIR2L4; sir2-like 4; SIR2-like protein 4; SIRT4; sirtuin 4; sirtuin type 4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23409, 304539, 75387
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 6.79 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q8R216, Q9Y6E7
• Gene Symbols: SIRT4
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 29-313 of human SIRT4 (NP_0363721).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG