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SIRT5 Monoclonal Antibody (OTI 1G9), TrueMAB™, OriGene
SDP

Catalog No. 501674213
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50-167-4213 100 μL
50-254-1007 30 μL
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Catalog No. 50-167-4213 Supplier OriGene Supplier No. TA503279
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Description

Mouse Monoclonal Antibody

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.

Specifications

Antigen SIRT5
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI 1G9
Concentration 0.61 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene SIRT5
Gene Accession No. Q9NXA8
Gene Alias SIR2L5
Gene Symbols SIRT5
Host Species Mouse
Immunogen Full length human recombit protein of human SIRT5 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23408
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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