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SIRT5 Monoclonal Antibody (OTI2C4), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA503233

Encompass_Preferred

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Catalog No. 50-167-4181


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Description

Description

SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.
Specifications

Specifications

SIRT5
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q9NXA8
SIRT5
Full length human recombit protein of human SIRT5 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI2C4
Unconjugated
SIRT5
SIR2L5
Mouse
Affinity Chromatography
RUO
23408
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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