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SIRT5 Mouse anti-Human, Clone: OTI1B6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF503315

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
SIRT5 is a human member of a family of proteins called Sirtuins (Sir2-like proteins) and are present in prokaryotes and eukaryotes. All Sir2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast and mammalian sirtuins are able to metabolize NAD and possibly at as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated Sir2-mediated NAD metabolism and NAD-activated Sir2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of Sir2 with NAD and the N epsilon-acetyl-lysine groups of acetylated histones.Specifications
SIRT5 | |
Monoclonal | |
Unconjugated | |
SIRT5 | |
SIR2L5 | |
Mouse | |
Affinity Chromatography | |
RUO | |
23408 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI1B6 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q9NXA8 | |
SIRT5 | |
Full length human recombit protein of human SIRT5 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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