Invitrogen™ SIRT6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595240

Catalog No. PIPA595240

Description

Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human U87 whole cell, human A549 whole cell, human K562 whole cell, human U2OS whole cell, human Hela whole cell. IHC: Mouse Cardiac Muscle Tissue, Human Mammary Cancer Tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.

Specifications

• Antigen: SIRT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRT6
• Gene Alias: 2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; Sirt6; sirtuin 6; sirtuin type 6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50721, 51548
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P59941, Q8N6T7
• Gene Symbols: SIRT6
• Immunogen: E.coli-derived human SIRT6 recombinant protein (Position: D14-E180).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG