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Sirt6 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A302452AT

Encompass_Preferred

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Catalog No. 50-156-2622


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.
Specifications

Specifications

Sirt6
Polyclonal
TBS with 0.1% BSA and 0.09% sodium azide
Q8N6T7
SIRT6
Between 305 and 355
20 μL
Primary
Human
Antibody
IgG
Western Blot
Unconjugated
SIRT6
Mono-ADP-ribosyltransferase sirtuin-6, SIR2-like protein 6, Silent information regulator 2-like protein 6.
Rabbit
Antigen affinity chromatography
RUO
51548
4° C
Liquid
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