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SIRT6 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501728845 Shop All Proteintech Group Inc Products
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50-172-8845 150 μL
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Catalog No. 50-172-8845 Supplier Proteintech Group Inc Supplier No. 135721AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody raised against full length human SIRT6 antigen.

The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT6 is a histone H3 lysine 9 deacetylase and is thought to stabilize the DNA-dependent protein kinase at double-stranded DNA breaks and may have a role in the process of mammalian aging.

Specifications

Antigen SIRT6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SIRT6
Gene Accession No. P59941, Q8N6T7
Gene Alias SIR2 like protein 6, SIR2L6, SIRT6
Gene Symbols SIRT6
Host Species Rabbit
Immunogen SIRT6 Fusion Protein Ag4469
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 299638, 50721, 51548
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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