Invitrogen™ SIRT7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5139782

Catalog No. PIPA5139782

Description

Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user. Immunogen sequence: LVVYTGAGIS TAASIPDYRG PNGVWTLLQK GRSVSAADLS EAEPTLTHMS ITRLHEQKLV QHVVSQNCDG LHLRSGLPRT AISE.

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.

Specifications

• Antigen: SIRT7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRT7
• Gene Alias: MGC126840; MGC126842; NAD-dependent deacetylase sirtuin-7; NAD-dependent protein deacetylase sirtuin-7; NAD-dependent protein deacylase sirtuin-7; regulatory protein SIR2 homolog 7; silent mating type information regulation 2, S.cerevisiae, homolog 7; Sir2l7; SIR2-like protein 7; sir2-related protein type 7; Sirt7; sirtuin 7; sirtuin type 7; Unknown (protein for MGC:142712)
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51547
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NRC8
• Gene Symbols: SIRT7
• Immunogen: Recombinant protein corresponding to Human SIRT7. Recombinant protein control fragment (Product #RP-108766).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG