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SIRT7 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA146468
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PIPA146468 100 μL
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Catalog No. PIPA146468 Supplier Thermo Scientific Supplier No. PA146468

Description

Rabbit Polyclonal Antibody

The target sequence has 88% sequence homology with bovine and porcine and 82% sequence homology with drosophila. Suggested positive control: antigen standard for SIRT7 (transient overexpression lysate), human liver protein.

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SIRT7
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Gene SIRT7
Gene Accession No. Q9NRC8, Q8BKJ9
Gene Alias MGC126840 , MGC126842 , NAD dependent deacetylase sirtuin 7 , Silent mating type information regulation 2
Gene Symbols SIRT7
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues 100-200 of an internal portion of human SIRT7. [Swiss-ProtNo. Q9NRC8]
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 209011, 51547
Target Species Human, Mouse
Content And Storage 4° C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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