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Tocris Bioscience™ SIS3
GREENER_CHOICE

Catalog No. 529110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective Smad3 inhibitor; inhibits TGF-βR1 signaling

SIS3 is a selective Smad3 inhibitor; attenuates TGF-β1-dependent Smad3 phosphorylation and DNA binding. Has no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. Inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts. Also inhibits TGF-β2-induced endothelial cell differentiation in iPSCs.

Specifications

Quantity 10 mg
Product Type SIS3
Purity 97%
Molecular Weight (g/mol) 489.99

For Research Use Only

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