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Tocris Bioscience™ SJ 1008066
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Catalog No. 75425
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5 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

MAGE-A11 inhibitor disrupts MAGE-A11:PCF11 interaction

SJ 1008066 is a cell permeable inhibitor of testis-restricted melanoma antigen protein MAGE-A11 (IC50 = 0.13 μM). SJ 1008066 binds to the MAGE homology domain (MHD) and disrupts MAGE-A11:PCF11 interaction. SJ1008066 exhibits no effect on MAGE-A3:AMPKα1 or MAGE-F1:MMS19 interactions in TR-FRET and cell lysate pulldown assays.

Specifications

Chemical Name or Material N1-((1 H-Indol-5-yl)methyl)-N3-(quinolin-4-yl)propane-1,3-diamine
Quantity 5 mg
Target Ubiquitin Ligase (E3) Inhibitors
Molecular Formula C21H22N4
Purity 98%
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