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  5. Tocris Bioscience™ SJPYT 310

Tocris Bioscience™ SJPYT 310
SDP

Catalog No. 883910 Shop All R&D Systems Products
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88-391-0 10 mg
88-395-0 50 mg
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Catalog No. 88-391-0 Supplier Tocris Bioscience™ Supplier No. 8839/10
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Description

Potent and selective PXR antagonist

SJPYT 310 is a potent and selective PXR antagonist (IC50 values are 4 and 9 nM for binding and cellular activity, respectively). SJPYT 310 displays selectivity for hPXR without affecting the activity of mPXR, hCAR, hFXR, hLXRα, or hVDR. SJPYT 310 shows no toxicity.

Specifications

Chemical Name or Material N-[5-(1,1-Dimethylethyl)-2-[(1S)-1-methylbutoxy]phenyl]-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
CAS 2883814-84-2
Quantity 10 mg
Target PXR/NR1I2
Molecular Formula C27H36N4O3
Purity 98%
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