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  5. Tocris™ SK 609

Tocris™ SK 609

Catalog No. 703925
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Dopamine D3 receptor biased agonist

SK 609 is a dopamine D3 receptor biased agonist. Preferentially signals via the G protein-dependent pathway (EC50 values for G protein and β-arrestin-dependent signaling are 1.1 and 50.2 μM, respectively). Exhibits selectivity for D3 over D2 receptors. Improves motor deficits in rodent Parkinson's disease models and ameliorates L-DOPA (Cat. No. 3788) induced abnormal involuntary movements.

Specifications

Chemical Name or Material 2-chloro-α-methyl-benzenepropanamine hydrochloride
CAS 1092797-77-7
Quantity 25 mg
Target Dopamine D3 Receptor Agonists
Molecular Formula C10H14ClN.HCl
Formula Weight 3333
Purity 98%
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