Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIMA512542

Skeletal Muscle Actin Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1)), Invitrogen™

Catalog No. PIMA512542
Change view
Click to view available options
Quantity:
500 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIMA512542 500 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIMA512542 Supplier Thermo Scientific Supplier No. MA512542

Description

Mouse Monoclonal Antibody

MA5-12542 targets Actin Skeletal Muscle in IF and IHC (P) applications and shows reactivity with Amphibian, Bovine, Guinea Pig, Human, Ovine, Rabbit, and Rat samples. The MA5-12542 immunogen is n-terminal decapeptide.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Skeletal Muscle Actin
Applications Immunocytochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone 5C5.F8.C7 (alpha-Sr-1)
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Acta1
Gene Accession No. P62736, P62737, P62738, P62739, P62740, P68133, P68134, P68135, P68136, P68138
Gene Alias 0610041G09Rik; AA959943; AAT6; ACTA; Acta1; ACTA1 protein; Acta2; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha actin; alpha actin 2; Alpha-actin-1; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; GIG46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin; unnamed protein product
Gene Symbols Acta1, ACTA2
Host Species Mouse
Immunogen N-terminal decapeptide
Purification Method Ammonium sulfate precipitation
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009271, 100009506, 100716933, 100722917, 101107662, 101121051, 11459, 11475, 281592, 29437, 515610, 58, 59, 81633
Target Species Amphibian, Bovine, Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgM κ
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.