Skeletal Muscle Actin Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1)), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA512542

Catalog No. PIMA512542

Description

MA5-12542 targets Actin Skeletal Muscle in IF and IHC (P) applications and shows reactivity with Amphibian, Bovine, Guinea Pig, Human, Ovine, Rabbit, and Rat samples. The MA5-12542 immunogen is n-terminal decapeptide.

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

Specifications

• Antigen: Skeletal Muscle Actin
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P62736, P62737, P62738, P62739, P62740, P68133, P68134, P68135, P68136, P68138
• Gene Symbols: Acta1, ACTA2
• Immunogen: N-terminal decapeptide
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Amphibian, Bovine, Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat
• Product Type: Antibody
• Isotype: IgM κ

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
• Clone: 5C5.F8.C7 (alpha-Sr-1)
• Conjugate: Unconjugated
• Gene: Acta1
• Gene Alias: 0610041G09Rik; AA959943; AAT6; ACTA; Acta1; ACTA1 protein; Acta2; Acta-2; actin alpha 1; actin alpha 1, skeletal muscle; actin alpha 2, smooth muscle; actin, alpha 1, skeletal muscle; actin, alpha 2, smooth muscle, aorta; actin, alpha skeletal muscle; Actin, alpha skeletal muscle, intermediate form; actin, alpha, vascular smooth muscle; actin, aortic smooth muscle; Actin, aortic smooth muscle, intermediate form; Acts; ACTSA; Actsk-1; Actvs; alpha actin; alpha actin 2; Alpha-actin-1; Alpha-actin-2; alpha-cardiac actin; alphaSMA; alpha-smooth muscle actin; ASMA; a-SMA; cell growth-inhibiting gene 46 protein; CFTD; CFTD1; CFTDM; cytoplasmic beta-actin; GIG46; hypothetical protein LOC515610; LOW QUALITY PROTEIN: actin, alpha skeletal muscle; LOW QUALITY PROTEIN: actin, aortic smooth muscle; MPFD; MYMY5; NEM1; NEM2; NEM3; nemaline myopathy type 3; SHPM; SMalphaA; smooth muscle alpha-actin; unnamed protein product
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 100009271, 100009506, 100716933, 100722917, 101107662, 101121051, 11459, 11475, 281592, 29437, 515610, 58, 59, 81633
• Content And Storage: 4° C
• Form: Liquid