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SKI 178, Tocris Bioscience™
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Quantity:
50 mg
Description
Non-lipid sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.
Specifications
Specifications
Molecular Formula | C21H22N4O4 |
Quantity | 50 mg |
InChI Key | GMFUWEBOUKIKRP-LPYMAVHISA-N |
SMILES | CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC |
IUPAC Name | N-[(E)-1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide |
Molecular Weight (g/mol) | 394.431 |
PubChem CID | 5342941 |
Percent Purity | >98% |
Safety and Handling
Recommended Storage | Store at −20°C |
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