Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

SKI 178, Tocris Bioscience™

Catalog No. 545250
Click to view available options
Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Non-lipid sphingosine kinase 1 (SphK1) inhibitor

Non-lipid sphingosine kinase 1 (SphK1) inhibitor (IC50 = 0.1-1.8 μM). Induces CDK1-dependent apoptosis in human acute myeloid leukemia cell lines. Active in vivo.

Chemical Identifiers

Physical Form Solid
Synonym SKI 178
Solubility Information Soluble to 100mM in DMSO
Formula Weight 394.42
Linear Formula C21H22N4O4
CAS 1259484-97-3
Chemical Name or Material N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide

Specifications

Molecular Formula C21H22N4O4
Quantity 50 mg
InChI Key GMFUWEBOUKIKRP-LPYMAVHISA-N
SMILES CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)C3=CC(=C(C=C3)OC)OC
IUPAC Name N-[(E)-1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Molecular Weight (g/mol) 394.431
PubChem CID 5342941
Percent Purity >98%
Recommended Storage Store at −20°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.