Invitrogen™ SKP1 Recombinant Rabbit Monoclonal Antibody (10G5X5)

Catalog No.	Quantity
PIMA535746	100 μL

Catalog No. PIMA535746 Supplier Invitrogen™ Supplier No. MA535746

Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: HHKDDPPPPE DDENKEKRTD DIPVWDQEFL KVDQGTLFEL ILAANYLDIK GLLDVTCKTV ANMIKGKTPE EIRKTFNIKN DFTEEEEAQV RKENQWCEEK.

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteasome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.

Specifications

• Antigen: SKP1
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 10G5X5
• Concentration: 0.25 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: SKP1
• Gene Accession No.: P63208, Q6PEC4, Q9WTX5
• Gene Alias: 15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like
• Gene Symbols: SKP1, Skp1a
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 64-163 of human SKP1 (P63208).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 21402, 287280, 6500
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG