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Invitrogen™ SKP1 Recombinant Rabbit Monoclonal Antibody (JM27-37)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA532744

Catalog No. PIMA532744


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Description

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteasome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SKP1
Recombinant Monoclonal
1 mg/mL
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
P63208, Q6PEC4, Q9WTX5
SKP1, Skp1a
Synthetic peptide within Human Skp1 aa 106-155.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
JM27-37
Unconjugated
SKP1
15kDa; 2610043E24Rik; 2610206H23Rik; cyclin A/CDK2-associated p19; cyclin A/CDK2-associated protein p19; cyclin-A/CDK2-associated protein p19; EMC19; MGC34403; OCP2; OCP-2; OCP-II; OCP-II protein; organ of Corti protein 2; Organ of Corti protein II; p19A; p19Skp1; polypeptide 1-like; RNA polymerase II elongation factor-like protein; RNA polymerase II elongation factor-like protein OCP2; SIII; Skp1; Skp1a; S-phase kinase-associated protein 1; S-phase kinase-associated protein 1A; TCEB1L; transcription elongation factor B polypeptide 1-like
Rabbit
Protein A
RUO
21402, 287280, 6500
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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