Invitrogen™ SLAIN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA544942

Catalog No. PIPA544942

Description

Peptide sequence: LSAKSGGGPG SGPRRTSSEE LRDATSLLAA GEGGLLDEVE PLRPDELERL Sequence homology: Cow: 92%; Guinea Pig: 86%; Human: 100%; Mouse: 86%; Rabbit: 92%; Rat: 86%.

SLAIN2 is closely related to SLAIN1, a novel stem cell protein that is expressed at the stem cell and epiblast stages. Unlike SLAIN1, SLAIN2 is widely expressed and is thought to play a role in regulating microtubule (MT) growth and organization. SLAIN2 binds to end-binding proteins (EBs), cytoplasmic linker proteins (CLIPs) such as CLIP170, CLIP-associated proteins, and interacts with the MT polymerase ch-TOG. Depletion of SLAIN2 using RNAi led to disorganization of the radial MT array, indicating its importance in the regulation of MT growth and organization.

Specifications

• Antigen: SLAIN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLAIN2
• Gene Alias: 5033405K12Rik; 8030444K12Rik; AI596370; FLJ21611; hypothetical protein LOC534203; KIAA1458; LOW QUALITY PROTEIN: SLAIN motif-containing protein 2; RGD1311593; SLAIN motif family member 2; SLAIN motif family, member 2; SLAIN motif-containing protein 2; SLAIN2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 57606
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q9P270
• Gene Symbols: SLAIN2
• Immunogen: Synthetic peptide directed towards the N-terminal of human SLAIN2 (aa 71-120).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov