SLAMF6 (CD352) Mouse anti-Human, PE, Clone: hSF6.4.20, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 566378

Catalog No. BDB566378

Description

The hSF6.4.20 monoclonal antibody specifically binds to SLAM family member 6 (SLAMF6) which is also known as CD352, NK-T-B-antigen (NTB-A), or Activating NK receptor. CD352 is a ñ60 kDa type I transmembrane glycoprotein that contains two ITSMs (immunoreceptor tyrosine-based switch motifs) in its cytoplasmic domain and belongs to the CD2 subfamily of the immunoglobulin superfamily. CD352 is expressed by thymocytes, NK cells, B cells, and T cells. CD352 functions through homophilic interactions as a coreceptor for the activation of NK cellsand lymphocytes. It plays roles in regulating various cellular effector functions including cytolytic activity, production of cytokines such as IFN-γ and IL-17, and immunoglobulin class switching

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.

Specifications

• Antigen: SLAMF6 (CD352)
• Clone: hSF6.4.20
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

• Classification: Monoclonal
• Conjugate: PE
• Gene Alias: SLAMF6, NTBA, NTB-A, NKTB-antigen, SLAM family memb. 6, KALI, SF2000, Ly108
• Immunogen: Human SLAMF6 Transfected Cell Line
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.