SLAMF6 (CD352) Mouse anti-Human, PE, Clone: hSF6.4.20, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 566378
The hSF6.4.20 monoclonal antibody specifically binds to SLAM family member 6 (SLAMF6) which is also known as CD352, NK-T-B-antigen (NTB-A), or Activating NK receptor. CD352 is a ñ60 kDa type I transmembrane glycoprotein that contains two ITSMs (immunoreceptor tyrosine-based switch motifs) in its cytoplasmic domain and belongs to the CD2 subfamily of the immunoglobulin superfamily. CD352 is expressed by thymocytes, NK cells, B cells, and T cells. CD352 functions through homophilic interactions as a coreceptor for the activation of NK cellsand lymphocytes. It plays roles in regulating various cellular effector functions including cytolytic activity, production of cytokines such as IFN-γ and IL-17, and immunoglobulin class switchingR-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
|Mouse IgG1, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|SLAMF6, NTBA, NTB-A, NKTB-antigen, SLAM family memb. 6, KALI, SF2000, Ly108|
|Human SLAMF6 Transfected Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.|
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