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SLAMF6 (CD352) Mouse anti-Human, PE, Clone: hSF6.4.20, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 566378

Catalog No. BDB566378


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Description

Description

The hSF6.4.20 monoclonal antibody specifically binds to SLAM family member 6 (SLAMF6) which is also known as CD352, NK-T-B-antigen (NTB-A), or Activating NK receptor. CD352 is a ñ60 kDa type I transmembrane glycoprotein that contains two ITSMs (immunoreceptor tyrosine-based switch motifs) in its cytoplasmic domain and belongs to the CD2 subfamily of the immunoglobulin superfamily. CD352 is expressed by thymocytes, NK cells, B cells, and T cells. CD352 functions through homophilic interactions as a coreceptor for the activation of NK cellsand lymphocytes. It plays roles in regulating various cellular effector functions including cytolytic activity, production of cytokines such as IFN-γ and IL-17, and immunoglobulin class switching

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
Specifications

Specifications

SLAMF6 (CD352)
PE
Affinity Purified
Murine
Mouse IgG1, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
hSF6.4.20
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
SLAMF6, NTBA, NTB-A, NKTB-antigen, SLAM family memb. 6, KALI, SF2000, Ly108
Human SLAMF6 Transfected Cell Line
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
RUO
Primary
Human
Documents
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