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SLAMF7 Mouse anti-Human, Clone: OTI3B3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF807414

Catalog No. 50-166-8265


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Specifications

Specifications

SLAMF7
Monoclonal
Unconjugated
SLAMF7
Lyophilized
SLAMF7
Full length human recombit protein of human SLAMF7 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI3B3
PBS with 8% trehalose and no preservative; pH 7.3
Q9NQ25
19A, CD319, CRACC, CS1
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
57823
SDS
Documents
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