Invitrogen™ SLC10A2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552108

Catalog No. PIPA552108

Description

Immunogen sequence: NKAEIPESKE NGTEPESSFY KANGGFQPDE Highest antigen sequence identity to the following orthologs: Mouse - 47%, Rat - 42%.

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

Specifications

• Antigen: SLC10A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc10a2
• Gene Alias: Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; ileal Na(+)/bile acid cotransporter; ileal sodium/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; ISBAT; ISBT; Na(+)-dependent ileal bile acid transporter; NTCP2; PBAM; Slc10a2; Sodium/taurocholate cotransporting polypeptide, ileal; sodium/taurocholate-cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2; solute carrier family 10 member 2; solute carrier family 10, member 2
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6555
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q12908
• Gene Symbols: Slc10a2
• Immunogen: Recombinant protein corresponding to Human SLC10A2. Recombinant protein control fragment (Product #RP-101763).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG