Invitrogen™ SLC10A2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518990

Catalog No. PIPA518990

Description

This antibody is predicted to react with rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); mutations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).

Specifications

• Antigen: SLC10A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Slc10a2
• Gene Alias: Apical sodium-dependent bile acid transporter; ASBT; IBAT; ileal apical sodium-dependent bile acid transporter; ileal Na(+)/bile acid cotransporter; ileal sodium/bile acid cotransporter; Ileal sodium-dependent bile acid transporter; ISBAT; ISBT; Na(+)-dependent ileal bile acid transporter; NTCP2; PBAM; Slc10a2; Sodium/taurocholate cotransporting polypeptide, ileal; sodium/taurocholate-cotransporting polypeptide, ileal; solute carrier family 10 (sodium/bile acid cotransporter family), member 2; solute carrier family 10 (sodium/bile acid cotransporter), member 2; solute carrier family 10 member 2; solute carrier family 10, member 2
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 20494
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P70172
• Gene Symbols: Slc10a2
• Immunogen: Synthetic peptide sequence (DETNKGFQPDEK) corresponding to the C-terminus amino acids of Slc10a2 (aa 337-348).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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