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Invitrogen™ SLC11A1 Polyclonal Antibody
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Catalog No. PIPA542412
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100 μL
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PIPA542412 100 μL
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Catalog No. PIPA542412 Supplier Invitrogen™ Supplier No. PA542412
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Description

Rabbit Polyclonal Antibody

Peptide sequence: GYEYVVARPE QGALLRGLFL PSCPGCGHPE LLQAVGIVGA IIMPHNIYLH Sequence homology: Cow: 86%; Goat: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Rabbit: 93%; Rat: 86%; Sheep: 86%.

NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC11A1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SLC11A1
Gene Accession No. P49279
Gene Alias Bcg; host resistance locus Bcg/Ity/Lsh; integral membrane protein; Itg; Ity; Lsh; natural resistance associated macrophage protein; natural resistance associated macrophage protein 1; natural resistance-associated macrophage protein; natural resistance-associated macrophage protein 1; natural resistance-associated macrophages protein 1; NRAMP; NRAMP 1; Nramp1; Slc11a1; solute carrier 11 family member 1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1; solute carrier family 11 (sodium/phosphate symporters), member 1; solute carrier family 11 A1; solute carrier family 11 member 1; solute carrier family 11 member a1
Gene Symbols SLC11A1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human SLC11A1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6556
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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