Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ SLC11A1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA5107258
Description
Sequence homology: Cow: 100%; Dog: 93%; Goat: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 93%.
NRAMP1, also known as SLC11A1, is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as leprosy and tuberculosis, and inflammatory diseases such as Crohn disease and rheumatoid arthritis. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Specifications
SLC11A1 | |
Polyclonal | |
Unconjugated | |
SLC11A1 | |
Bcg; host resistance locus Bcg/Ity/Lsh; integral membrane protein; Itg; Ity; Lsh; natural resistance associated macrophage protein; natural resistance associated macrophage protein 1; natural resistance-associated macrophage protein; natural resistance-associated macrophage protein 1; natural resistance-associated macrophages protein 1; NRAMP; NRAMP 1; Nramp1; Slc11a1; solute carrier 11 family member 1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1; solute carrier family 11 (sodium/phosphate symporters), member 1; solute carrier family 11 A1; solute carrier family 11 member 1; solute carrier family 11 member a1 | |
Rabbit | |
Protein A | |
RUO | |
6556 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
1 mg/mL | |
PBS with 2% sucrose and 0.09% sodium azide; pH 7.4 | |
P49279 | |
SLC11A1 | |
Synthetic peptide directed towards the C-terminal region of human SLC11A1. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction