Invitrogen™ SLC12A6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA580005

Catalog No. PIPA580005

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat brain tissue, rat C6 whole cell, mouse brain tissue. IHC: human colorectal adenocarcinomar tissue.

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy.

Specifications

• Antigen: SLC12A6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC12A6
• Gene Alias: 9530023I19Rik; ACCPN; DKFZP434D2135; Electroneutral potassium-chloride cotransporter 3; furosemide-sensitive KCl cotransporter 3; gaxp; Kcc3; KCC3A; KCC3B; K-Cl cotransporter 3; potassium chloride cotransporter 3; potassium chloride cotransporter KCC3a-S3; potassium-chloride transporter-3a; potassium-chloride transporter-3b; SLC12A6; solute carrier family 12 (potassium/chloride transporter), member 6; solute carrier family 12 (potassium/chloride transporters), member 6; solute carrier family 12 member 6; solute carrier family 12, member 6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 107723, 691209, 9990
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: Q924N4, Q9UHW9
• Gene Symbols: SLC12A6
• Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human SLC12A6 (1060-1080aa QKAKSMEGFQDLLNMRPDQSN).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG