Invitrogen™ SLC15A1 Polyclonal Antibody

Catalog No.	Quantity
PIPA551747	100 μL

Catalog No. PIPA551747 Supplier Invitrogen™ Supplier No. PA551747

Description

Rabbit Polyclonal Antibody

Immunogen sequence: DKTLPVFPKG NEVQIKVLNI GNNTMNISLP GEMVTLGPMS QTNAFMTFDV NKLTRINISS PGSPVTAVTD DFKQGQRHTL LVWAPNHYQV VKDGLNQKPE KGENGIRFVN TFNELITITM SGKVYANISS YNA Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 72%.

In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins. PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues. Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential. PEPT1 is 708 amino acid protein that contains 12 putative membrane-spanning domains. PEPT1 is expressed in Caco-2 cells. PEPT1 seems to play important roles in nutritional and pharmacological therapies. The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.

Specifications

• Antigen: SLC15A1
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: SLC15A1
• Gene Accession No.: P46059
• Gene Alias: Caco-2 oligopeptide transporter; D630032F02; HPECT1; HPEPT1; Intestinal H(+)/peptide cotransporter; intestinal H+/peptide cotransporter; intestinal peptide transporter PEPT1; macrophage oligopeptide transporter PEPT1; oligopeptide transporter, small intestine isoform; PECT1; Pept1; PEPT-1; Peptide transporter 1; peptide transporter PepT1; pineal gland-specific PEPT1; proton-coupled dipeptide cotransporter; proton-dependent gastrointestinal peptide transporter 1; Slc15a1; solute carrier family 15 (oligopeptide transporter), member 1; solute carrier family 15 member 1
• Gene Symbols: SLC15A1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human SLC15A1. Recombinant protein control fragment (Product #RP-101759).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6564
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG