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Invitrogen™ SLC15A1 Polyclonal Antibody
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Catalog No. PIPA5101733
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PIPA5101733 100 μL
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Catalog No. PIPA5101733 Supplier Invitrogen™ Supplier No. PA5101733
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SLC15A1.

In mammalian small intestine, the proton-coupled peptide transporter (PEPT) is responsible for the absorption of small peptides arising from digestion of dietary proteins. PEPT1, a hydrogen ion/peptide cotransporter, transports dipeptides and tripeptides, but not free amino acids or peptides with more than three amino acid residues. Its driving force for uphill transport requires proton binding and the presence of an inside-negative membrane potential. PEPT1 is 708 amino acid protein that contains 12 putative membrane-spanning domains. PEPT1 is expressed in Caco-2 cells. PEPT1 seems to play important roles in nutritional and pharmacological therapies. The mammalian kidney expresses a proton-coupled peptide transporter, PEPT2, that is responsible for the absorption of small peptides, as well as beta-lactam antibiotics and other peptide-like drugs, from the tubular filtrate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC15A1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SLC15A1
Gene Accession No. P46059, P51574, Q9JIP7
Gene Alias Caco-2 oligopeptide transporter; D630032F02; HPECT1; HPEPT1; Intestinal H(+)/peptide cotransporter; intestinal H+/peptide cotransporter; intestinal peptide transporter PEPT1; macrophage oligopeptide transporter PEPT1; oligopeptide transporter, small intestine isoform; PECT1; Pept1; PEPT-1; Peptide transporter 1; peptide transporter PepT1; pineal gland-specific PEPT1; proton-coupled dipeptide cotransporter; proton-dependent gastrointestinal peptide transporter 1; Slc15a1; solute carrier family 15 (oligopeptide transporter), member 1; solute carrier family 15 member 1
Gene Symbols SLC15A1
Host Species Rabbit
Immunogen A synthesized peptide derived from human SLC15A1(Accession P46059), corresponding to amino acid residues K224-I274.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117261, 56643, 6564
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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