Invitrogen™ SLC16A13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106681

Catalog No. PIPA5106681

Description

Antibody detects endogenous levels of total MOT13.

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.

Specifications

• Antigen: SLC16A13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC16A13
• Gene Alias: 1700007D07Rik; MCT 13; MCT13; monocarboxylate transporter; Monocarboxylate transporter 13; monocarboxylic acid transporter 13; MOT13; Slc16a13; solute carrier family 16 (monocarboxylic acid transporters), member 13; solute carrier family 16 member 13; solute carrier family 16, member 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 201232, 287451, 69309
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q66HE2, Q7RTY0, Q8CE94
• Gene Symbols: SLC16A13
• Immunogen: A synthesized peptide derived from human SLC16A13(Accession Q7RTY0), corresponding to amino acid residues P392-D426.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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