Invitrogen™ SLC16A3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587977

Catalog No. PIPA587977

Description

Positive Samples: HT-1080, SW620, MCF7, Rat skeletal muscle; Cellular Location: Cell membrane, Multi-pass membrane protein Immunogen sequence: IRKKPKEPQP EVAAAEEEKL HKPPADSGVD LREVEHFLKA EPEKNGEVVH TPETSV.

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).

Specifications

• Antigen: SLC16A3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC16A3
• Gene Alias: MCT 3; MCT 4; MCT3; MCT-3; Mct4; MCT-4; MGC138472; MGC138474; monocarboxylate transporter; monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4; Slc16a3; solute carrier family 16 (monocarboxylate transporter), member 3; solute carrier family 16 (monocarboxylic acid transporters), member 3; solute carrier family 16 member 3; solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 80878, 80879, 9123
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.9 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: O15427, O35910, P57787
• Gene Symbols: SLC16A3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 410-465 of human MCT4/SLC16A3 (NP_0041981).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG